Prazosin and priapism.
نویسندگان
چکیده
منابع مشابه
Insights of priapism mechanism and rationale treatment for recurrent priapism.
Priapism is defined as abnormal prolonged penile erection occurring beyond or unrelated to sexual interest. The disorder is enigmatic yet devastating because of its elusive etiology, irreversible erectile tissue damage, and resultant erectile dysfunction (ED). Current management strategies suffer from a poor understanding of the pathophysiology, especially at the molecular level. The traditiona...
متن کاملPriapism: pathophysiology and management
Introduction. Priapism is defined as a persistent erection of the penis not accompanied by sexual desire or stimulation and can be a urological emergency. There are three different types of priapism: low-flow priapism, highflow priapism and recurrent priapism. Unfortunately, clinical guideline does not establish a fixed set of rules for the treatment of this condition. Methods. This review comb...
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Prazosin, a potent and selective alpha-adrenergic antagonist, was given by inhalation to nine asthmatic subjects aged 25-48 years (six with positive skin tests). Prazosin 0.5 mg, salbutamol 1 mg, or placebo were given by nebuliser in randomised double-blind fashion on separate days. Although all subjects showed a significant increase in FEV1, vital capacity, and maximum expiratory flow at 70% o...
متن کاملEffects of Prazosin
The left ventricular (LV) and coronary vascular effects of prazosin, a drug that reduces peripheral vascular resistance by blocking postsynaptic a receptors, were examined in conscious dogs. Prazosin, 0.07 mg/kg/mmn i.v. for 7 minutes, induced sustained hypotensive effects for more than 12 hours. The peak effects occurred 3045 minutes after administration. Prazosin increased heart rate by 28 ± ...
متن کاملAripiprazole-induced priapism
Priapism is a urologic emergency representing a true disorder of penile erection that persists beyond or is unrelated to sexual interest or stimulation. A variety of psychotropic drugs are known to produce priapism, albeit rarely, through their antagonistic action on alpha-1 adrenergic receptors. We report such a case of priapism induced by a single oral dose of 10 mg aripiprazole, a drug with ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1979
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6197.1039